Article

Effects of cardiac glycoside digoxin on dendritic spines and motor learning performance in mice

2023-02-28

Abstract excerpt

Synapse formation following the generation of postsynaptic dendritic spines is essential for motor learning and functional recovery after brain injury. The C -terminal fragment of agrin cleaved by neurotrypsin induces dendritic spine formation in the adult hippocampus. Since the α 3 subunit of sodium-potassium ATPase (Na/K ATPase) is a neuronal receptor for agrin in the central nervous system, cardiac glycosides m...

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Literature Corpus work: 8c08ece5-39f6-5f61-9442-266795a17d21
DOI: 10.21203/rs.3.rs-2592611/v1

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