Article

Spectrum graph-based de-novo sequencing algorithm MaxNovo achieves high peptide identification rates in collisional dissociation MS/MS spectra

2021-09-06

Abstract excerpt

We describe MaxNovo, a novel spectrum graph-based peptide de-novo sequencing algorithm integrated into the MaxQuant software. It identifies complete sequences of peptides as well as sequence tags that are incomplete at one or both of the peptide termini. MaxNovo searches for the highest-scoring path in a directed acyclic graph representing the MS/MS spectrum with peaks as nodes and edges as potential sequence cons...

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Literature Corpus work: b55df6d1-b36c-56f2-911a-4ebbfca4c453
DOI: 10.1101/2021.09.04.458985

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