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Highly reliable GIGA-sized synthetic human therapeutic antibody library construction

27 Apr 2023

Abstract excerpt

Background Monoclonal antibodies (mAbs) and their derivatives are the fastest expanding category of pharmaceuticals. Efficient screening and generation of appropriate therapeutic human antibodies are important and urgent issues in the field of medicine. The successfulin vitrobiopanning method for antibody screening largely depends on the highly diverse, reliable and humanized CDR library. To rapidly obtain potent...

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Share to Advanced Biosensing Techniques and Applications
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37180155
DOI: 10.3389/fimmu.2023.1089395

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