Article

Characterization of Histone Lysine β-hydroxybutyrylation in bovine tissues, cells, and cumulus-oocyte complexes

2021-09-08

Abstract excerpt

<h4>ABSTRACT</h4> Besides their canonical roles as energy sources, short-chain fatty acids act as metabolic regulators of gene expression through the histone post-translational modifications. The ketone body β-hydroxybutyrate (BHB) was shown to cause a novel type of epigenetic modification, Histone Lysine β-hydroxybutyrylation (Kbhb), associated with genes upregulated in starvation-responsive metabolic pathways....

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Literature Corpus work: 8bea49a6-3b01-5351-9c3a-415cefa67003
DOI: 10.1101/2021.09.07.459289

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