Article

High histone crotonylation modification in bovine fibroblasts promotes cell proliferation and the developmental efficiency of preimplantation nuclear transfer embryos

2024-01-24

Abstract excerpt

<title>Abstract</title> <p>Lysin crotonylation (Kcr), a recently discovered histone acylation modification, is intricately related to gene expression, cell proliferation, maintenance of stem cell pluripotency, and regulation of various biological processes, symbolizing gene transcriptional activity. During cell culture, the introduction of exogenous croconic acid disodium salt (Nacr) has been shown to modulate in...

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Literature Corpus work: e32735ce-5bef-5887-b52e-4a24f55e4851
DOI: 10.21203/rs.3.rs-3873199/v1

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