Article

Functionally Mature Bioengineered Human Skeletal Muscle Tissues Capture Essential Aspects of Glucose Metabolism

2026-01-16

Abstract excerpt

<h4>ABSTRACT</h4> Human skeletal muscle is a major regulator of whole-body metabolic homeostasis, yet mechanistic insight into human muscle plasticity is limited by the lack of in vitro models with adult-like metabolic and functional maturity. Here, we develop a workflow for generating bioengineered human skeletal muscle tissues that undergo coordinated structural, molecular, and functional maturation and stabili...

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Literature Corpus work: 8b66ada3-0e3d-5ebc-8633-e046d7bfa46e
DOI: 10.64898/2026.01.16.698404

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