Article

Training-induced bioenergetic improvement in human skeletal muscle is associated with non-stoichiometric changes in the mitochondrial proteome without reorganization of respiratory chain content

2021-02-22

Abstract excerpt

<h4>SUMMARY</h4> Mitochondrial defects are implicated in multiple diseases and aging. Exercise training is an accessible and inexpensive therapeutic intervention improving mitochondrial bioenergetics and quality of life. By combining a multi-omics approach with biochemical and in silico normalization, we removed the bias arising from the training-induced increase in human skeletal muscle mitochondrial content to...

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Literature Corpus work: 078a5cff-cfa2-5e94-bdd8-4ff92be57183
DOI: 10.1101/2021.02.19.431993

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