Article

Age, Sex, and Genetics Influence the Abundance of Infiltrating Immune Cells in Human Tissues

2019-04-19

Abstract excerpt

Despite infiltrating immune cells playing an essential role in human disease and the patient response to treatment, the central mechanisms influencing variability in infiltration patterns are unclear. Using bulk RNA-seq data from 53 GTEx tissues, we applied cell-type deconvolution algorithms to evaluate the immune landscape across the healthy human body. We first performed a differential expression analysis of inf...

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Literature Corpus work: 8b1ecc40-5e67-5320-b06b-c2d6b4646900
DOI: 10.1101/614305

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