Article
Gut Microbiota Dysbiosis Remodels the Multi-Tissue Transcriptional Landscape of the Host
2026-05-25
Abstract excerpt
<title>Abstract</title> <p> Background The gut microbiota exerts a profound influence on host physiology, but its systemic impact on gene expression across diverse tissues remains poorly characterized. Results This study investigated the transcriptional effects of gut microbiota depletion and restoration in mice across six tissues (colon, jejunum, liver, heart, lung, and kidney) using whole-transcriptome seque...
Topics
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- Barrier Structure and Function Studies
- Cancer Immunotherapy and Biomarkers
- Clostridium difficile and Clostridium perfringens research
- Epigenetics and DNA Methylation
- Ferroptosis and cancer prognosis
- Gut microbiota and health
- Helicobacter pylori-related gastroenterology studies
- Pancreatic and Hepatic Oncology Research
Identifiers and source
- Literature Corpus work
- 8b17a91d-d1aa-533a-aad6-94d0e0703d90
- DOI
- 10.21203/rs.3.rs-9079459/v1
