Article

Shared and disease-specific host gene-microbiome interactions across human diseases

2021-03-30

Abstract excerpt

While the gut microbiome and host gene regulation separately contribute to gastrointestinal disorders, it is unclear how the two may interact to influence host pathophysiology. Here, we developed a machine learning-based framework to jointly analyze host transcriptomic and microbiome profiles from 416 colonic mucosal samples of patients with colorectal cancer, inflammatory bowel disease, and irritable bowel syndro...

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Literature Corpus work: 1fba5986-c41f-58ba-9f16-de2a04dc184b
DOI: 10.1101/2021.03.29.437589

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