Article

Tissue-dependent transcriptional and bacterial associations in primary sclerosing cholangitis-associated inflammatory bowel disease

2022-11-04

Abstract excerpt

<h4>Background: </h4> Patients with primary sclerosing cholangitis (PSC) frequently have co-ocurring ulcerative colitis (UC) and develop colorectal cancer. Colorectal cancer risk in patients with PSC-associated ulcerative colitis (PSC/UC) is elevated relative to patients with ulcerative colitis (UC) alone, reasons for which remain obscure. Understanding the molecular and microbial basis for differences between the...

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Literature Corpus work: ecec2086-a5df-59e8-91ba-037f1176d8b3
DOI: 10.12688/wellcomeopenres.16901.2

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