Article

Endothelial deletion of <i>p53</i> generates transitional endothelial cells and improves lung development during neonatal hyperoxia

2024-05-08

Abstract excerpt

<h4>ABSTRACT</h4> Bronchopulmonary dysplasia (BPD), a prevalent and chronic lung disease affecting premature newborns, results in vascular rarefaction and alveolar simplification. Although the vasculature has been recognized as a main player in this disease, the recently found capillary heterogeneity and cellular dynamics of endothelial subpopulations in BPD remain unclear. Here, we show Cap2 cells are damaged du...

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Literature Corpus work: 8afb2cc7-bf99-526a-9297-330ecd51542b
DOI: 10.1101/2024.05.07.593014

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