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Single cell transcriptomic analysis of bloodstream form <i>Trypanosoma brucei</i> reconstructs cell cycle progression and differentiation via quorum sensing

2020-12-11

Abstract excerpt

The life cycles of African trypanosomes are dependent on several differentiation steps, where parasites transition between replicative and non-replicative forms specialised for infectivity and survival in mammal and tsetse fly hosts. Here, we use single cell transcriptomics (scRNA-seq) to dissect the asynchronous differentiation of replicative slender to transmissible stumpy bloodstream form Trypanosoma brucei ....

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Literature Corpus work
cfe46e2e-8368-548d-a89e-3b17efcfd9dd
DOI
10.1101/2020.12.11.420976
Open publication

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Single cell transcriptomic analysis of bloodstream form <i>Trypanosoma brucei</i> reconstructs cell cycle progression and differentiation via quorum sensingDOI 10.1101/2020.12.11.420976
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