Article

Droplet-based whole genome amplification: a novel approach for sequencing minute amounts of Mycobacterium tuberculosis DNA

2023-11-29

Abstract excerpt

<title>Abstract</title> Implementation of whole genome sequencing (WGS) for patient care is hindered by limited <italic>Mycobacterium tuberculosis</italic> (<italic>Mtb</italic>) in clinical specimens and slow <italic>Mtb</italic> growth. We evaluated droplet multiple displacement amplification (dMDA) for amplification of minute amounts of <italic>Mtb</italic> DNA to enable WGS as an alternative to other <ital...

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Literature Corpus work: 8aecd2bd-2f1f-5c0a-b78c-01e6e4340e19
DOI: 10.21203/rs.3.rs-3655355/v1

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