Article

Genomic Sequencing from Sputum for Tuberculosis Disease Diagnosis, Lineage Determination and Drug Susceptibility Prediction

2022-10-31

Abstract excerpt

<h4>Background</h4> Universal access to drug susceptibility testing for newly diagnosed tuberculosis patients is recommended. Access to culture-based diagnostics remains limited and targeted molecular assays are vulnerable to emerging resistance conferring mutations. Improved sample preparation protocols for direct-from-sputum sequencing of Mycobacterium tuberculosis would accelerate access to comprehensive drug...

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Literature Corpus work: 4aca68a8-f441-5e99-947c-7df0b5ac9a84
DOI: 10.1101/2022.10.31.514503

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