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Direct nanopore sequencing of <i>M. tuberculosis</i> on sputa and rescue of suboptimal results to enhance transmission surveillance

2025-09-25

Abstract excerpt

<h4>Summary</h4> Whole-genome sequencing (WGS) enhances precision in predicting antimicrobial resistance and tracking Mycobacterium tuberculosis (MTB) transmission. Due to MTB’s slow-growing nature, genomic results are delayed; however, few efforts have sought to accelerate them by performing WGS directly on respiratory specimens. Most culture-free efforts have focused on accelerating resistance prediction. The...

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Literature Corpus work
c8e18732-8364-5a53-871e-5b98b9cb5ea3
DOI
10.1101/2025.09.23.678181
Open publication

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Direct nanopore sequencing of <i>M. tuberculosis</i> on sputa and rescue of suboptimal results to enhance transmission surveillanceDOI 10.1101/2025.09.23.678181
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