Back to search

Article

Nanopore sequencing for <i>Mycobacterium tuberculosis</i> drug susceptibility testing and outbreak investigation

2022-03-08

Abstract excerpt

<h4>Background</h4> Mycobacterium tuberculosis whole-genome sequencing (WGS) using Illumina technology has been widely adopted for genotypic drug susceptibility testing (DST) and outbreak investigation. Oxford Nanopore Technologies is reported to have higher error rates but has not been thoroughly evaluated for these applications. <h4>Methods</h4> We analyse 151 isolates from Madagascar, South Africa and Englan...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e88334e9-ee9b-58a2-acb4-f187f3a64aff
DOI
10.1101/2022.03.04.22271870
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Nanopore sequencing for <i>Mycobacterium tuberculosis</i> drug susceptibility testing and outbreak investigationDOI 10.1101/2022.03.04.22271870
Evaluation of Nanopore sequencing for Mycobacterium tuberculosis drug susceptibility testing and outbreak investigation: a genomic analysisSemantic proximity
Long-read sequencing of <i>Mycobacterial tuberculosis</i> is comparable to short-read sequencing for antimicrobial resistance prediction and epidemiological studiesSemantic proximity
Direct nanopore sequencing of <i>M. tuberculosis</i> on sputa and rescue of suboptimal results to enhance transmission surveillanceSemantic proximity
Genomic Sequencing from Sputum for Tuberculosis Disease Diagnosis, Lineage Determination and Drug Susceptibility PredictionSemantic proximity
Targeted Sequencing Workflows for Comprehensive Drug Resistance Profiling of <i>Mycobacterium tuberculosis</i> cultures using Illumina MiSeq and Nanopore MinION: Comparison of analytical and diagnostic performance, turnaround time and costSemantic proximity
Rapid and economical drug resistance profiling with Nanopore MinION for clinical specimens with low bacillary burden of Mycobacterium tuberculosisSemantic proximity
Compact Targeted Next-Generation Sequencing for Rapid Diagnosis of Drug-Resistant Tuberculosis using Minimum BiocontainmentSemantic proximity
The MAGMA pipeline for comprehensive genomic analyses of clinical <i>Mycobacterium tuberculosis</i> samplesSemantic proximity
Rapid Identification of Drug-Resistant Tuberculosis Genes Using Direct PCR Amplification and Oxford Nanopore Technology SequencingSemantic proximity
Assessing Nanopore Sequencing for Clinical Diagnostics: a Comparison of Next-Generation Sequencing (NGS) Methods for Mycobacterium tuberculosisSemantic proximity
Field evaluation of nanopore targeted next-generation sequencing to predict drug-resistant tuberculosis from native sputum in South Africa and ZambiaSemantic proximity
Validation of an optimised Oxford Nanopore sequencing workflow versus Illumina for mycobacteria from primary MGIT cultureSemantic proximity
Select a neighboring publication to make it the new centre.