Article

Targeting fatty acid synthase suppresses tumor development in <i>NF2/CDKN2A</i> -deficient malignant pleural mesothelioma

2024-07-17

Abstract excerpt

Malignant pleural mesothelioma (MPM) is an uncommon yet deadly cancer linked to asbestos exposure. The lack of effective early diagnosis and treatment leads to reduced life expectancy among patients with MPM. This study is aimed to identify a novel molecular target inhibitor to develop more effective therapeutics for MPM. Our drug screening assay showed that the fatty acid synthase (FASN) inhibitor cerulenin demon...

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Literature Corpus work: 8ad26fc7-62cc-5050-a5b1-db18aeea8ed7
DOI: 10.1101/2024.07.14.603191

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