Article

Genome-wide discovery of somatic coding and regulatory variants in Diffuse Large B-cell Lymphoma

2017-12-12

Abstract excerpt

Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer originating from mature B-cells. Many known driver mutations are over-represented in one of its two molecular subgroups, knowledge of which has aided in the development of therapeutics that target these features. The heterogeneity of DLBCL determined through prior genomic analysis suggests an incomplete understanding of its molecular aetiology, with a l...

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Literature Corpus work: 8ac9c92e-f6e3-5b90-a552-6a96a19c350f
DOI: 10.1101/225870

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