Article

Biophysical Characterisation of Human LincRNA-p21 Sense and Antisense Alu Inverted Repeats

2021-12-08

Abstract excerpt

Human Long Intergenic Noncoding RNA-p21 (LincRNA-p21) is a regulatory noncoding RNA that plays an important role in promoting apoptosis. LincRNA-p21 is also critical in down-regulating many p53 target genes through its interaction with a p53 repressive complex. The interaction between LincRNA-p21 and the repressive complex is likely dependent on the RNA tertiary structure. Previous studies have determined the two-...

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Literature Corpus work: 8a72d6cb-3c30-5f2b-b396-787bea22f390
DOI: 10.1101/2021.12.08.471813

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