Article

Mitochondrial aberrations in systemic lupus erythematosus pathogenesis: Insights and therapeutic implications

2024-04-16

Abstract excerpt

Abstract Systemic lupus erythematosus (SLE), a chronic autoimmune disease, is marked by impaired immune tolerance and heightened activity in both innate and adaptive immune systems. Hallmarks of SLE include elevated type I interferons and autoantibody production, though the exact causes of SLE remain elusive despite advances in research techniques. Crucial to SLE research is understanding its pathogenesis and deve...

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Literature Corpus work: 8a5397c8-f173-580f-9e37-e3ced6f7bd68
DOI: 10.1002/rai2.12119

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