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Mitochondrial dysfunction drives natural killer cell dysfunction in systemic lupus erythematosus

2025-01-28

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by immune dysregulation and widespread inflammation. Natural killer (NK) cells, essential for immune surveillance, exhibit profound dysfunction in SLE, including impaired cytotoxicity and cytokine production. However, the mechanisms underlying these abnormalities remain poorly understood. This st...

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Literature Corpus work
6a3cdf04-83ea-5c08-b728-bd3eb773eb4c
DOI
10.1101/2025.01.28.25321013
Open publication

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Mitochondrial dysfunction drives natural killer cell dysfunction in systemic lupus erythematosusDOI 10.1101/2025.01.28.25321013
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