Article
Immunometabolism in the pathogenesis of systemic lupus erythematosus: an update
19 Aug 2020
Abstract excerpt
PURPOSE OF REVIEW: To provide an update on state-of-the-art evidence on the role of immunometabolism reprogramming in the pathogenesis of systemic lupus erythematosus (SLE). RECENT FINDINGS: Mitochondrial dysfunction and enhanced oxidative stress, along with specific defects in other metabolic pathways, can promote dysregulation of innate and adaptive immune responses in SLE. These abnormalities appear to be...
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