Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNA

10 May 2019

Abstract excerpt

The mitochondrion supplies energy to the cell and regulates apoptosis. Unlike other mammalian organelles, mitochondria are formed by binary fission and cannot be directly produced by the cell. They contain numerous copies of a compact circular genome that encodes RNA molecules and proteins involved in mitochondrial oxidative phosphorylation. Whereas mitochondrial DNA (mtDNA) activates the innate immune system if...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to interferon and immune responses
Share to Systemic Lupus Erythematosus Research
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31134086
DOI: 10.3389/fimmu.2019.01026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Autoantibodies in Systemic Lupus Erythematosus Target Mitochondrial RNAPMID 31134086Read ↗

Anti-mitochondrial autoantibodies in systemic lupus erythematosus and their association with disease manifestationsSemantic proximity Read ↗

Mitochondrial aberrations in systemic lupus erythematosus pathogenesis: Insights and therapeutic implicationsSemantic proximity Read ↗

Mitochondria as a key player in systemic lupus erythematosusSemantic proximity Read ↗

The Role of Mitochondria in Systemic Lupus Erythematosus: A Glimpse of Various Pathogenetic MechanismsSemantic proximity Read ↗

Circulating mitochondrial DNA copy numbers represent a sensitive marker for diagnosis and monitoring of disease activity in systemic lupus erythematosusSemantic proximity Read ↗

Lower circulating mitochondrial DNA and increased mitokines suggest significant mitochondrial dysfunction in systemic lupus erythematosus with renal involvementSemantic proximity Read ↗

Mitochondrial impairment and repair in the pathogenesis of systemic lupus erythematosusSemantic proximity Read ↗

Neutrophil Extracellular Trap Mitochondrial DNA and Its Autoantibody in Systemic Lupus Erythematosus and a Proof‐of‐Concept Trial of MetforminSemantic proximity Read ↗

Screening for Mitochondrial tRNA Variants in 200 Patients with Systemic Lupus Erythematosus.Semantic proximity Read ↗

Leukocyte Mitochondrial DNA Alteration in Systemic Lupus Erythematosus and Its Relevance to the Susceptibility to Lupus NephritisSemantic proximity Read ↗

Circulating microparticles in systemic Lupus Erythematosus.Semantic proximity Read ↗

Mitochondrial DNA damage is associated with damage accrual and disease duration in patients with Systemic Lupus ErythematosusSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.