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MYORG and STRADB as Activity-Dependent Therapeutic Targets for Frailty Prevention: Discovery and Cross-Cohort Validation in Aging Skeletal Muscle

2026-04-21

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Skeletal muscle aging exhibits substantial heterogeneity, with some individuals maintaining robust function into advanced age while others develop sarcopenia and frailty. Whether molecular signatures distinguishing these trajectories reflect biological aging or modifiable factors, such as physical activity, remains unclear. <h4>Methods</h4> An integrated discovery-validatio...

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Literature Corpus work
fe173647-9395-5433-9e8f-097cf76eeec6
DOI
10.64898/2026.04.18.719222
Open publication

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MYORG and STRADB as Activity-Dependent Therapeutic Targets for Frailty Prevention: Discovery and Cross-Cohort Validation in Aging Skeletal MuscleDOI 10.64898/2026.04.18.719222
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