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Integrative analysis reveals therapeutic potential of pyrvinium pamoate in Merkel cell carcinoma

2023-11-04

Abstract excerpt

Merkel Cell Carcinoma (MCC) is an aggressive neuroendocrine cutaneous malignancy arising from either ultraviolet-induced mutagenesis or Merkel cell polyomavirus (MCPyV) integration. Despite extensive research, our understanding of the molecular mechanisms driving the transition from normal cells to MCC remains limited. To address this knowledge gap, we assessed the impact of inducible MCPyV T antigens on normal hu...

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Literature Corpus work
89dedd22-3ebf-5843-ba25-a0ff7ed9053c
DOI
10.1101/2023.11.01.565218
Open publication

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Integrative analysis reveals therapeutic potential of pyrvinium pamoate in Merkel cell carcinomaDOI 10.1101/2023.11.01.565218
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