Article

The Novel LSD1 Inhibitor ZY0511 Suppresses Diffuse Large B Cell Lymphoma Proliferation by Inducing Apoptosis and Autophagy

2021-06-03

Abstract excerpt

<title>Abstract</title> <p>Lysine-specific demethylase 1 (LSD1, also known as KDM1A) is an attractive agent for treatment of cancer. Nevertheless, the anti-tumor effect of LSD1 inhibitors against diffuse large B-cell lymphoma (DLBCL) and the underlying mechanism are still unclear. Here, we report that <italic>KDM1A</italic> is overexpressed in human DLBCL tissues, and negatively related to overall survival rate i...

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Literature Corpus work: 89bfae81-7c6b-5223-b580-635c32983bb4
DOI: 10.21203/rs.3.rs-578853/v1

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