Article

DCZ0014, A Novel Compound in the Therapy of Diffuse Large B-Cell Lymphoma via the B Cell Receptor Signaling Pathway

2020-08-01

Abstract excerpt

<h4>Background: </h4> Diffuse large B cell lymphoma (DLBCL) is a clinical and genetically heterogeneous lymphoid malignancy. Although the R-CHOP (rituximab plus cyclophosphamide, vincristine, doxorubicin, and prednisone) treatment can improve the survival rate of patients with DLBCL. However, more than 30% of patients exhibit treatment failure, relapse, or refractory disease. Therefore, novel drugs or targeted the...

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Literature Corpus work: 0792881a-135b-5acc-856b-e3760911411c
DOI: 10.21203/rs.3.rs-48447/v1

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