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LSD1 Demethylates and Destabilizes Autophagy Protein LC3B in Ovarian Cancer

29 Oct 2024

Abstract excerpt

Autophagy is a complex cellular process that can either promote or inhibit cancer progression and development, depending on the context and molecular regulation involved. This study investigates how LSD1 regulates autophagy in ovarian cancer by interacting with the autophagy protein LC3B. Utilizing the bioinformatic analysis of TCGA, CPTAC, and GEO datasets, as well as immunohistochemistry in ovarian cancer...

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Share to Autophagy in Disease and Therapy
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PMID: 39595554
DOI: 10.3390/biom14111377

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