Article

Select Gene Expression Across Variable PrPSc Permissive Ovine Microglia

2019-08-26

Abstract excerpt

<title>Abstract</title> <p>Abstract Abstract Background: Transmissible spongiform encephalopathies (TSEs) are a group of fatal, neurodegenerative diseases that affect multiple species, including sheep, cattle, and humans. A misfolded, pathogenic isoform (PrPD) of the normal, host-encoded, cellular prion protein (PrPC) is the causative agent for TSEs. While there have been advances in understanding TSEs, antemo...

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Literature Corpus work: 899ab65d-d3e2-5318-9341-5776f2f08462
DOI: 10.21203/rs.2.13583/v1

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