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Article

Differential expression of Prnp and Sprn in scrapie infected sheep also reveals Prnp genotype specific differences.

Biochemical and biophysical research communications - 23 Jan 2009

Gossner A G, Bennet N, Hunter N, Hopkins J

Abstract excerpt

The central role for PrP in the pathogenesis of the transmissible spongiform encephalopathies (TSEs) is illustrated by the resistance of Prnp(0/0) mice to disease and by the inverse association of Prnp gene dosage with incubation period. Understanding the role of PrP(C) in TSEs necessitates knowledge of expression levels of the Prnp gene during the development of disease. SSBP/1 scrapie shows a defined pattern of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19070601
DOI: 10.1016/j.bbrc.2008.12.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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