Article

The coordination between CTCF, cohesin and TFs impacts nucleosome repositioning and chromatin insulation to define state specific 3D chromatin folding

2024-11-03

Abstract excerpt

CTCF-mediated chromatin folding plays a key role in gene regulation, however the mechanisms controlling chromatin organization across cell states are not fully elucidated. Comprehensive analyses reveal that CTCF binding stability and cohesin overlap in mice and humans, are regulated by species specific differences in CTCF binding site (CBS) accessibility and enrichment of motifs corresponding to expressed TFs. By...

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Identifiers and source

Literature Corpus work: 8974fe6d-509e-5ef8-bde4-3f54fd1d2e54
DOI: 10.1101/2024.11.02.620823

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