Article

Loss of Signal Transducer and Activator of Transcription 3 Impaired the Osteogenesis of Mesenchymal Progenitor Cells in Vivo and in Vitro

2021-05-27

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Signal transducer and activator of transcription 3 (Stat3) is a cytoplasmic transcription factor that participates in various biologic processes. Loss of Stat3 causes hyperimmunoglobulin E syndrome, presenting with skeletal disorders including osteoporosis, recurrent fractures, scoliosis, and craniosynostosis. The objective of this study is to explore the effect...

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Literature Corpus work: 893e2b6e-0907-50a2-a35f-7a4ef0b7a80d
DOI: 10.21203/rs.3.rs-530012/v1

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