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Loss of signal transducer and activator of transcription 3 impaired the osteogenesis of mesenchymal progenitor cells in vivo and in vitro

2021-04-02

Abstract excerpt

<title>Abstract</title> <p>Background Signal transducer and activator of transcription 3 (Stat3) is a cytoplasmic transcription factor that participates in various biologic processes. Loss of Stat3 causes hyperimmunoglobulin E syndrome, presenting with skeletal disorders including osteoporosis, recurrent fractures, scoliosis, and craniosynostosis. The objective of this study is to explore the effect and mechanis...

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Literature Corpus work
dd7b0fe5-e2e3-552d-9103-ac472c5d8680
DOI
10.21203/rs.3.rs-355218/v1
Open publication

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Loss of signal transducer and activator of transcription 3 impaired the osteogenesis of mesenchymal&nbsp;progenitor cells&nbsp;in vivo&nbsp;and&nbsp;in vitroDOI 10.21203/rs.3.rs-355218/v1
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