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Article

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model.

Journal of visualized experiments : JoVE - 3 Jul 2020

Yang Yiling, Chen Qianye, Zhou Siru, Gong Xinyi, Xu Hongyuan, Hong Yueyang, Dai Qinggang, Jiang Lingyong

Abstract excerpt

Transgenic mouse models are powerful for understanding the critical genes controlling osteoclast differentiation and activity, and for studying mechanisms and pharmaceutical treatments of osteoporosis. Cathepsin K (Ctsk)-Cre mice have been widely used for functional studies of osteoclasts. The signal transducer and activator of transcription 3 (STAT3) is relevant in bone homeostasis, but its role in osteoclasts...

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PMID: 32716374
DOI: 10.3791/61390

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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