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Article

JAK-STAT and bone metabolism

5 Apr 2013

Abstract excerpt

Emerging evidences suggest Janus kinase (JAK)-signal transducer and activator of transcription (STAT) signaling pathway plays an important role in bone development and metabolism. Effects of JAK-STAT pathway on skeletal development are summarized based on skeletal phenotype of individual JAK and STAT gene knockout mouse. Furthermore, STAT3 has more profound effects on bone homeostasis compared with the other...

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Identifiers

PMID: 24069548
DOI: 10.4161/jkst.23930

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