Article
A critical role for interleukin-6 family-mediated Stat3 activation in osteoblast differentiation and bone formation.
Bone - 1 Sept 2006
Itoh Shousaku, Udagawa Nobuyuki, Takahashi Naoyuki, Yoshitake Fumio, Narita Hiroko, Ebisu Shigeyuki, Ishihara Katsuhiko
Abstract excerpt
Signal transduction and activator of transcription (Stat) 3 is a transcription factor that is activated by a variety of cytokines and growth factors, including IL-6 family cytokines. These cytokines regulate bone homeostasis and have been reported to regulate the differentiation of osteoblasts an...
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