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MNase profiling of promoter chromatin in <i>S. typhimurium</i> -stimulated GM12878 cells reveals dynamic and response-specific nucleosome architecture

2019-10-24

Abstract excerpt

The nucleosome is the primary unit of chromatin structure and commonly imputed as a regulator of nuclear events, although the exact mechanisms remain unclear. Recent studies have shown that certain nucleosomes can have different sensitivities to micrococcal nuclease (MNase) digestion, resulting in the release of populations of nucleosomes dependent on the concentration of MNase. Mapping MNase sensitivity of nucleo...

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Literature Corpus work
893dc235-23fc-56b8-9d7f-9731a1200ad6
DOI
10.1101/816348
Open publication

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MNase profiling of promoter chromatin in <i>S. typhimurium</i> -stimulated GM12878 cells reveals dynamic and response-specific nucleosome architectureDOI 10.1101/816348
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