Article

DNA Methylation by Restriction Modification Systems Affects the Global Transcriptome Profile in <i>Borrelia burgdorferi</i>

2018-07-24

Abstract excerpt

<h4>ABSTRACT</h4> Prokaryote restriction modification (RM) systems serve to protect bacteria from potentially detrimental foreign DNA. Recent evidence suggests that DNA methylation by the methyltransferase (MTase) components of RM systems can also have effects on transcriptome profiles. The causative agent of Lyme disease, Borrelia burgdorferi , encodes two RM systems with N6-Methyladenosine (m6A) MTase activity...

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Literature Corpus work: f46826cd-bbc4-5f39-adc2-6749e13ab8c3
DOI: 10.1101/375352

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