Back to search

Article

Elucidating DNA-binding protein dynamics in <i>Salmonella</i> Typhimurium within macrophages using a breakthrough low-input ChIP-exo approach

2024-06-22

Abstract excerpt

Genome-wide identification of binding profiles for DNA-binding proteins in Salmonella Typhimurium within macrophages is crucial for understanding virulence gene expression and cellular processes. However, this task remains challenging due to the limited amount of intracellular bacterial cells. Here, we present ChIP-mini, a low-input ChIP-exo utilizing 5,000-fold reduced number of initial bacterial cells and analy...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d3889dbf-fe12-51ff-ad03-50862f2850f5
DOI
10.1101/2024.06.20.599816
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Elucidating DNA-binding protein dynamics in <i>Salmonella</i> Typhimurium within macrophages using a breakthrough low-input ChIP-exo approachDOI 10.1101/2024.06.20.599816
RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella TyphimuriumSemantic proximity
Multimodal temporal mapping of macrophage transcriptome remodeling during <i>Salmonella</i> infectionSemantic proximity
Intramacrophage RIL-seq uncovers an RNA antagonist of the <i>Salmonella</i> virulence-associated small RNA PinTSemantic proximity
SalmonAct Deciphers Transcription Factor Regulatory Activity in <i>Salmonella</i> TranscriptomicsSemantic proximity
<i>Yersinia</i> remodels epigenetic histone modifications in human macrophagesSemantic proximity
Niche-specific profiling reveals transcriptional adaptations required for the cytosolic lifestyle of <i>Salmonella enterica</i>Semantic proximity
Pathogenic bacteria experience pervasive RNA polymerase backtracking during infectionSemantic proximity
Integrative Transcriptomic and Network Analysis Reveals Small Open Reading Frames as Regulators of DNA Methylation-Linked Pathogenicity and Adaptability in <i>Leptospira interrogans</i>Semantic proximity
Deep genome annotation of the opportunistic human pathogen <i>Streptococcus pneumoniae</i> D39Semantic proximity
PneumoBrowse 2: An integrated visual platform for curated genome annotation and multiomics data analysis of <i>Streptococcus pneumoniae</i>Semantic proximity
Integrative profiling of early host chromatin accessibility responses in human neutrophils with sensitive pathogen detectionSemantic proximity
Chromatin accessibility dynamics of <i>Chlamydia</i> -infected epithelial cellsSemantic proximity
Select a neighboring publication to make it the new centre.