Back to search

Article

EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in <i>Pseudomonas aeruginosa</i>

2024-01-10

Abstract excerpt

<h4>ABSTRACT</h4> The human pathogen Pseudomonas aeruginosa poses a major risk for a range of severe infections, particularly lung infections in patients suffering from cystic fibrosis (CF). As previously reported, the virulent behavior of this pathogen is enhanced by elevated levels of Ca 2+ that are commonly present in CF nasal and lung fluids. In addition, a Ca 2+ -binding EF-hand protein, EfhP (PA4107), wa...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
88fc87a4-f38e-55d4-89aa-0dba3a831d6a
DOI
10.1101/2024.01.09.574892
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
EF-Hand Calcium Sensor, EfhP, Controls Transcriptional Regulation of Iron Uptake by Calcium in <i>Pseudomonas aeruginosa</i>DOI 10.1101/2024.01.09.574892
The Pseudomonas aeruginosa PAO1 Two-Component Regulator CarSR Regulates Calcium Homeostasis and Calcium-Induced Virulence Factor Production through Its Regulatory Targets CarO and CarPSemantic proximity
The Cyclic AMP Receptor Protein Regulates Quorum Sensing and Global Gene Expression in <i>Yersinia pestis</i> During Planktonic Growth and Growth in BiofilmsSemantic proximity
Calprotectin protects <i>Staphylococcus aureus</i> in coculture with <i>Pseudomonas aeruginosa</i> by attenuating quorum sensing and decreasing the production of pseudomonal antimicrobialsSemantic proximity
The response regulator BqsR/CarR controls ferrous iron (Fe <sup>2+</sup> ) acquisition in <i>Pseudomonas aeruginosa</i>Semantic proximity
Analysis of <i>Pseudomonas aeruginosa</i> transcription in an <i>ex vivo</i> cystic fibrosis sputum model identifies metal restriction as a gene expression stimulusSemantic proximity
Zinc Starvation Drives Respiratory Remodeling and Metabolic Adaptations Associated with Cystic Fibrosis in <i>Pseudomonas aeruginosa</i>Semantic proximity
carP, encoding a Ca2+-regulated putative phytase, is evolutionarily conserved in Pseudomonas aeruginosa and has potential as a biomarker.Semantic proximity
A novel non-catalytic function of PA2803-encoded PcrP contributes to polymyxin B resistance in P. aeruginosa and redefines the functional role of the PA2803 subfamily.Semantic proximity
Determination of the Two-Component Systems regulatory network reveals core and accessory regulations across <i>Pseudomonas aeruginosa</i> lineagesSemantic proximity
Exploring aggregation genes in a <i>P. aeruginosa</i> chronic infection modelSemantic proximity
Transcription inhibitors with XRE DNA-binding and cupin signal-sensing domains drive metabolic diversification in <i>Pseudomonas</i>Semantic proximity
The Pseudomonas aeruginosa AlgZR two-component system coordinates multiple phenotypes.Semantic proximity
Select a neighboring publication to make it the new centre.