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Analysis of <i>Pseudomonas aeruginosa</i> transcription in an <i>ex vivo</i> cystic fibrosis sputum model identifies metal restriction as a gene expression stimulus

2023-08-21

Abstract excerpt

Chronic Pseudomonas aeruginosa lung infections are a distinctive feature of cystic fibrosis (CF) pathology, that challenge adults with CF even with the advent of highly effective modulator therapies. Characterizing P. aeruginosa transcription in the CF lung and identifying factors that drive gene expression could yield novel strategies to eradicate infection or otherwise improve outcomes. To complement published...

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Literature Corpus work
7cd1327c-b0be-5220-a5c4-6c480235fc11
DOI
10.1101/2023.08.21.554169
Open publication

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Analysis of <i>Pseudomonas aeruginosa</i> transcription in an <i>ex vivo</i> cystic fibrosis sputum model identifies metal restriction as a gene expression stimulusDOI 10.1101/2023.08.21.554169
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