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Calprotectin protects <i>Staphylococcus aureus</i> in coculture with <i>Pseudomonas aeruginosa</i> by attenuating quorum sensing and decreasing the production of pseudomonal antimicrobials

2025-04-14

Abstract excerpt

Pseudomonas aeruginosa and Staphylococcus aureus cause debilitating polymicrobial infections in diverse patient populations. Studies of these bacterial pathogens in coculture have shown that environmental variables including Fe availability and the host-defense protein calprotectin (CP) impact coculture dynamics. To decipher how CP modulates interactions between P. aeruginosa and S. aureus , we employed dual-sp...

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Literature Corpus work
f72a7bb4-bfdd-564d-938d-8566b822c077
DOI
10.1101/2025.04.14.648724
Open publication

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Calprotectin protects <i>Staphylococcus aureus</i> in coculture with <i>Pseudomonas aeruginosa</i> by attenuating quorum sensing and decreasing the production of pseudomonal antimicrobialsDOI 10.1101/2025.04.14.648724
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