Article

The response regulator BqsR/CarR controls ferrous iron (Fe <sup>2+</sup> ) acquisition in <i>Pseudomonas aeruginosa</i>

2025-04-12

Abstract excerpt

Pseudomonas aeruginosa is a ubiquitous, Gram-negative bacterium that forms biofilms and is responsible for antibiotic-resistant hospital-acquired infections in humans. The P. aeruginosa BqsRS two-component system regulates biofilm formation and dispersal by sensing extracytoplasmic Fe 2+ , but the mechanistic details of this process are poorly understood. In this work, we report the crystal and solution structur...

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Literature Corpus work: b0e20c7e-d96a-5861-a43e-26282650d7ea
DOI: 10.1101/2025.04.12.648518

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