Back to search

Article

Zinc Starvation Drives Respiratory Remodeling and Metabolic Adaptations Associated with Cystic Fibrosis in <i>Pseudomonas aeruginosa</i>

2026-07-17

Abstract excerpt

Host nutritional immunity restricts microbial growth by altering metal availability. In patients with cystic fibrosis (CF), microorganisms inhabiting the thick airway mucus experience severe nutrient limitation, particularly zinc (Zn) restriction, which plays a critical role in limiting lung colonization. However, Pseudomonas aeruginosa, a major contributor to morbidity and mortality in CF, employs multiple strat...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
5afa9371-70c1-5528-9957-d5da5c685e7b
DOI
10.64898/2026.07.15.738699
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Zinc Starvation Drives Respiratory Remodeling and Metabolic Adaptations Associated with Cystic Fibrosis in <i>Pseudomonas aeruginosa</i>DOI 10.64898/2026.07.15.738699
ZnuA and zinc homeostasis in Pseudomonas aeruginosaSemantic proximity
Pseudopaline-mediated zinc uptake by <i>Pseudomonas aeruginosa</i> determines specific clinically relevant phenotypes and infection outcomeSemantic proximity
Strategies for Zinc Uptake in Pseudomonas aeruginosa at the Host–Pathogen InterfaceSemantic proximity
Global stress response in <i>Pseudomonas aeruginosa</i> upon malonate utilizationSemantic proximity
Malonate is relevant to the lung environment and induces genome-wide stress responses in Pseudomonas aeruginosaSemantic proximity
Systems-wide dissection of organic acid assimilation in <i>Pseudomonas aeruginosa</i> reveals a novel path to underground metabolismSemantic proximity
Growth of<i>Pseudomonas aeruginosa</i>in zinc poor environments is promoted by a nicotianamine‐related metallophoreSemantic proximity
Metabolism and Pathogenicity ofPseudomonas aeruginosaInfections in the Lungs of Individuals with Cystic FibrosisSemantic proximity
Calprotectin protects <i>Staphylococcus aureus</i> in coculture with <i>Pseudomonas aeruginosa</i> by attenuating quorum sensing and decreasing the production of pseudomonal antimicrobialsSemantic proximity
Biogeochemical Forces Shape the Composition and Physiology of Polymicrobial Communities in the Cystic Fibrosis LungSemantic proximity
Genome-wide survey of <i>Pseudomonas aeruginosa</i> PA14 reveals a role for the glyoxylate pathway and extracellular proteases in the limited utilization of mucinSemantic proximity
Analysis of <i>Pseudomonas aeruginosa</i> transcription in an <i>ex vivo</i> cystic fibrosis sputum model identifies metal restriction as a gene expression stimulusSemantic proximity
Select a neighboring publication to make it the new centre.