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The <i>Mycobacterium tuberculosis</i> Pup-proteasome system regulates nitrate metabolism through an essential protein quality control system

2018-11-14

Abstract excerpt

<h4>ABSTRACT</h4> The human pathogen Mycobacterium tuberculosis ( M. tuberculosis ) encodes a proteasome that carries out regulated degradation of bacterial proteins. It has been proposed that the proteasome contributes to nitrogen metabolism in M. tuberculosis , although this hypothesis had not been tested. Upon assessing M. tuberculosis growth in several nitrogen sources, we found that a mutant strain lacki...

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Literature Corpus work
88dc1716-900d-5e58-80d6-54ae8ad7d298
DOI
10.1101/470989
Open publication

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