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Article

Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .

PloS one - 6 Jan 2010

Festa Richard A, McAllister Fiona, Pearce Michael J, Mintseris Julian, Burns Kristin E, Gygi Steven P, Darwin K Heran

Abstract excerpt

Prokaryotic ubiquitin-like protein (Pup) in Mycobacterium tuberculosis (Mtb) is the first known post-translational small protein modifier in prokaryotes, and targets several proteins for degradation by a bacterial proteasome in a manner akin to ubiquitin (Ub) mediated proteolysis in eukaryotes. To determine the extent of pupylation in Mtb, we used tandem affinity purification to identify its "pupylome". Mass...

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Identifiers

PMID: 20066036
DOI: 10.1371/journal.pone.0008589
PMCID: PMC2797603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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