Functional Genomics Reveals Extended Roles of the <i>Mycobacterium tuberculosis</i> Stress Response Factor σ ^H

Abstract excerpt

Mycobacterium tuberculosis is one of the most successful pathogens of humankind. During infection, M. tuberculosis must cope with and survive against a variety of different environmental conditions. Sigma factors likely facilitate the modulation of the pathogen's gene expression in response to changes in its extracellular milieu during infection. sigma(H), an alternate sigma factor encoded by the M. tuberculosis...

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