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Article

Mycobacterium tuberculosis prcBA genes encode a gated proteasome with broad oligopeptide specificity.

Molecular microbiology - 1 Mar 2006

Lin Gang, Hu Guiqing, Tsu Christopher, Kunes Yune Z, Li Huilin, Dick Lawrence, Parsons Thomas, Li Ping, Chen Zhiqiang, Zwickl Peter, Weich Nadine, Nathan Carl

Abstract excerpt

Genes predicted to be associated with the putative proteasome of Mycobacterium tuberculosis (Mtb) play a critical role in defence of the bacillus against nitrosative stress. However, proteasomes are uncommon in eubacteria and it remains to be established whether Mtb's prcBA genes in fact encode a proteasome. We found that coexpression of recombinant PrcB and PrcA in Escherichia coli over a prolonged period at 37...

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PMID: 16468985
DOI: 10.1111/j.1365-2958.2005.05035.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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