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Article

Survival of mycobacteria depends on proteasome-mediated amino acid recycling under nutrient limitation.

The EMBO journal - 18 Aug 2014

Elharar Yifat, Roth Ziv, Hermelin Inna, Moon Alexandra, Peretz Gabriella, Shenkerman Yael, Vishkautzan Marina, Khalaila Isam, Gur Eyal

Abstract excerpt

Intracellular protein degradation is an essential process in all life domains. While in all eukaryotes regulated protein degradation involves ubiquitin tagging and the 26S-proteasome, bacterial prokaryotic ubiquitin-like protein (Pup) tagging and proteasomes are conserved only in species belonging to the phyla Actinobacteria and Nitrospira. In Mycobacterium tuberculosis, the Pup-proteasome system (PPS) is...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24986881
DOI: 10.15252/embj.201387076
PMCID: PMC4195762

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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